![]() ![]() Palatal petechiae are found on the hard and soft palate in 50% of young adults in the first few days of the illness.Ĭholestatic jaundice due to liver involvement is itchy, resulting in excoriations and bruising. However, re-exposure to the antibiotic may sometimes result in recurrence of rash years later. The rash usually resolves within a week of discontinuing the antibiotic.It affects extensor surfaces and pressure points, face, neck, trunk, palms, and soles.The drug eruption is an itchy maculopapular or morbilliform rash.Recent studies suggest the actual rate of this antibiotic rash is much lower than previously reported. These include ampicillin, azithromycin, amoxicillin, cephalosporins, tetracyclines, and macrolides such as erythromycin. May be morbilliform, papular, scarlatiniform, vesicular, or purpuricĪ more intense and extensive cutaneous eruption appears in up to 90% of patients with infectious mononucleosis 2–10 days after starting antibiotics.Is usually faint and non-itchy, appearing first on the trunk and upper arms, extending to involve the face and forearms.Affects 4.2 to 13% of patients who are not on antibiotics.The typical exanthem of infectious mononucleosis is an acute, generalised maculopapular rash. What are the mucocutaneous features of infectious mononucleosis? Lymphoproliferative and other autoimmune haematological diseases.Periorbital and eyelid oedema (Hoagland sign).Older adults are more likely to develop hepatomegaly and jaundice than adolescents.Overt hepatitis with jaundice and tender hepatomegaly occurs in 5-10%.Elevation of liver transaminases are common in up to 50%.Hepatomegaly is rarely clinically palpable although is often detected on ultrasound.Associated abdominal pain or discomfort. ![]() ![]() Splenomegaly (enlarged spleen), typically in the second and third weeks.gradual onset of low-grade fever, malaise, arthralgia, and myalgia.abrupt onset of severe sore throat with cervical lymphadenopathy.Children are often asymptomatic or presumed to have a non-specific viral infection. Infectious mononucleosis presents typically in 75% of young adults 15% have an atypical presentation, and infection in 10% is asymptomatic. The incubation period from contact until symptoms is usually 6-7 weeks. The clinical manifestations of infection are dependent on the interaction between virus and host immune system. What are the clinical features of infectious mononucleosis? Spread to children is presumed to be from parents or siblings who carry EBV and shed the virus intermittently. EBV can also be spread through blood and semen during sexual contact, blood transfusion, organ transplantation, and other procedures. The virus survives on an object while it remains moist. How is infectious mononucleosis transmitted?ĮBV is passed from person to person by saliva through intimate contacts such as kissing, or via objects such as a toothbrush or drinking glass. ![]()
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